Recombinant human EGF protein is a 6.3 kDa biologically active domain of human epidermal growth factor. Our recombinant EGF protein is expressed to the highest purity in E. coli and extensively tested, making it ideal for use in chemically-defined iPSC, ESC and organoid culture media. 

Recombinant human FGF10 protein is a 17 kDa non-glycosylated, bioactive domain of human fibroblast growth factor 10. Our high-purity FGF10 protein is produced in E. coli and purified to homogeneity. For use in organoid culture, ESC/iPSC differentiation, and for the study of epithelial to mesenchymal transition and tumor metastasis. 

Recombinant human FGF2 /bFGF protein (145 aa) is a highly bioactive, short–form variant of human fibroblast growth factor 2 protein. Our high-purity FGF2 protein is a reliable option for ES cell and iPSC maintenance, as well as iPSC/MSC proliferation and differentiation.

Recombinant human FGF2 / bFGF protein (154 aa) is a highly bioactive, long–form variant of human fibroblast growth factor 2 protein. Our recombinant FGF2 protein has been optimized for high-purity expression in E. coli, making it a reliable option for the regulation of ESC maintenance, as well as iPSC/MSC proliferation and differentiation.

Recombinant human Gremlin 1 protein has been optimized by our experts for exceptionally high-purity production and bioactivity.   Gremlin-1 is a BMP-inhibitor present in the natural intestinal niche and provides an animal-free substitute for Noggin in chemically-defined media for many ESC, iPSC and organoid culture systems. 

Recombinant human HGF (NK1) protein is a high purity NK1 isoform of human hepatocyte growth factor (HGF) that promotes efficient differentiation of human iPSCs to hepatocyte-like cells at just 10 ng/ml with highly homogeneous expression of the hepatic marker, HNF4α.  The highly scalable animal-free manufacture and enhanced bioactivity make this suitable for chemically-defined media and reproducible scale-up.

Recombinant human Noggin supports growth of organoids derived from epithelial tissues and iPSC and ESC differentiation. Noggin protein is a bone morphogenetic protein (BMP) family antagonist used in the culture of intestinal, pancreatic, lung and tumor-derived organoids; maintenance of embryonic stem cells and differentiation into neural lineages. Qkine recombinant human noggin protein is animal and carrier-protein free for highly reproducible results and use in chemically defined media.

Recombinant human R-spondin 1 protein (RSPO1) is a 13kDa highly pure, bioactive fragment of human R-spondin 1. Our recombinant human R-spondin 1 protein is animal-free and not glycosylated to ensure production of homogeneous protein and enhanced comparability between batches.

Recombinant human R-spondin 3 protein is a 17 kDa bioactive fragment of human R-spondin 3 protein comprised of the two cysteine-rich furin-like domains, which are essential for its activity in stem cell and organoid culture. Our recombinant R-spondin 3 has been purified to homogeneity and is animal-free to ensure batch to batch consistency when adding to chemically-defined culture media.

Recombinant mouse Noggin supports growth of organoids derived from mouse epithelial tissues and stem cell differentiation. Noggin protein is a bone morphogenetic protein (BMP) family antagonist used in the culture of intestinal, pancreatic, lung and tumor-derived organoids; maintenance of embryonic stem cells and differentiation into neural lineages. Qkine recombinant mouse noggin protein is animal and carrier-protein free for highly reproducible results and use in chemically defined media.

Recombinant zebrafish FGF2 protein (bFGF) is a 17 kDa biologically active domain of zebrafish fibroblast growth factor 2 protein, expressed in E. coli and purified to homogeneity. Our recombinant FGF2 protein is trusted by the Cambridge Stem Cell Institute, UK  to support the maintenance and differentiation of their stem cell cultures.