Growth factors & cytokines for neural stem cell research

hPSC-differentiation-neural-stem-cell

Neuroscience includes several areas of research such as molecular and cellular neuroscience, neurooncology, and developmental neuroscience. It seeks to understand the function or development of the nervous system in healthy conditions and in neurodegenerative diseases, neurological and psychiatric disorders, and brain cancer.

Although the field of neuroscience has made significant advancements in recent years, shedding light on many aspects of brain function, it is still challenged by the complexity of neural tissue and the availability of model systems. Advances in stem cell research have provided better models of the unique features of the brain using human induced pluripotent stem cells (hiPSCs). HiPSCs can be differentiated into many neural and glial cell types including cortical or dopaminergic neurons, astrocytes, and microglia. More complex 3D modelling using brain organoids can be generated to better recapitulate the environment of the brain and to study the cell-cell and cell-matrix interactions.

High-quality growth factors are essential for developing and maintaining robust, reproducible, and physiologically relevant neural cultures. Growth factors developed in an animal-free expression system have a higher lot-to-lot consistency and fewer contamination risks from viruses, prions, and other animal-derived ingredients. All growth factors and cytokines from Qkine pass stringent biochemical and bioactivity quality control testing, ensuring you complete confidence in the reagents for your neural stem cell cultures.

All our recombinant proteins are animal-free
& come with Bioactivity. Guaranteed.

Featured resources for neural stem cell culture

Poster

Organoid brochure

Human iPSC directed
differentiation poster

Technote

FGF2-G3 case study

VEGF 165 Technote

Blog

Lifetime - engineering underpinning medicine PhD studentship sponsored by Qkine

Designing biomimetic neural materials for 3D cell culture

Contact our expert team

Our dedicated team of stem cell specialists is available to answer any queries and to give expert support when required.

Publications

Experimental Dermatology 32, 1143–1155 (2023).

‘Human epidermis organotypic cultures, a reproducible system recapitulating the epidermis in vitro.’

Authors: Agarwal, R. et al.
Labs:  Emmanuel Contassot and Alexander A. Navarini, University of Basel

Noggin (Qk034)
FGF-10 (Qk003)

Preprint (2023)

Profiling human hypothalamic neurons reveals a candidate combination drug therapy for weight loss.’

Authors: Chen, H.-J. C. et al.
Labs: John C. Marioni, European Bioinformatics Institute and Florian T. Merkle, University of Cambridge

BDNF (Qk050)

Protocols (2023)

Differentiation of RGC Induced Neurons (RGC-iNs).’

Authors: Agarwal, D. & Wahlin, K.
Lab: Karl Wahlin, University of California San Diego

GDNF (Qk051)
BDNF (Qk050)

BMC Biology, 20:14  (2022)

‘Stem Cell-Derived Porcine Macrophages as a New Platform for Studying Host-Pathogen Interactions

Authors: Meek, S. et al.
Lab: Tom Burdon, University of Edinburgh

FGF-2 (bFGF) 154 aa (Qk027)

Int. J. Mol. Sci (2022)

‘Progesterone Receptor Modulates Extraembryonic Mesoderm and Cardiac Progenitor Specification during Mouse Gastrulation

Authors: Drozd, A. et al.
Lab: Elisabetta Ferretti, University of Copenhagen

FGF-2 (bFGF) 154 aa (Qk027)
BMP-4 (Qk038)

Nature, 609, 136–143 (2022)

‘Spatial profiling of early primate gastrulation in utero

Authors: Bergmann, S. et al.
Lab: Thorsten E. Boroviak, University of Cambridge

Noggin (Qk034)

Biotechnology Journal (2021)

‘Hydrostatic Pressure Promotes Chondrogenic Differentiation and Microvesicle Release from Human Embryonic and Bone Marrow Stem Cells

Authors: Luo, L, et al.
Lab: Alicia El Haj, University of Birmingham

FGF-2 (bFGF) 145 aa (Qk025)

Animal-free growth factors for neural stem cell research

We are confident that the quality and bioactivity of our recombinant proteins will ensure that you achieve your research goals. Our dedicated team of stem cell specialists is available to answer any queries you may have and to give expert support when required.