Growth factors & cytokines
for hepatocyte differentiation

Complete animal-free hepatocyte differentiation process

The complete set of fully animal-free growth factors for the differentiation of human pluripotent cells to hepatocytes is available. To ensure reproducibility of your endoderm differentiation protocols every lot is thoroughly tested for biochemical purity and bioactivity. Lot-specific quality control data and animal origin-free (AOF/ADCF) certificates are available to facilitate planning for the transition to pre-clinical studies and establishing future GMP-compliant processes.

Hepatocyte differentiation from iPSC protocol

All our recombinant proteins are animal-free
& come with Bioactivity. Guaranteed.

Featured resources for hepatocyte differentiation

Blog

Why should I use animal-free growth factors and cytokines?

Technote

BMP4 comparison with other suppliers: Qkine BMP4 is more potent

BMP-4 (Qk038) has enhanced bioactivity

Blog

The future of iPSC-derived pancreas and liver implants

Product focus

Enhanced hepatocyte differentiation using HGF natural isoform NK1

The NK1 isoform is the smallest naturally occurring splice variant of HGF, it comprises the HGF N-terminal and first kringle domain. This isoform promotes efficient differentiation of human iPSCs to hepatocyte-like cells at just 10 ng/ml, resulting in highly homogeneous expression of the hepatic marker, HNF4α. Qkine HGF NK1 is also completely animal-free (AOF), making it suitable for chemically defined media and reproducible scale-up.

Contact our expert team

Our dedicated team of stem cell specialists is available to answer any queries and to give expert support when required.

Animal-free growth factors for hepatocyte differentiation

We are confident that the quality and bioactivity of our recombinant proteins will ensure that you achieve your research goals. Our dedicated team of stem cell specialists is available to answer any queries you may have and to give expert support when required.