Recombinant Gremlin-1 protein, a BMP inhibitor, is optimised for exceptionally high purity production from E.coli. Animal-derived component free for defined media. Gremlin-1 can substitute for Noggin in several embryonic and induced-pluripotent stem cell and organoid culture systems including intestinal, liver, pancreatic and cancer organoids.
Optimised human recombinant R-spondin 1 (Qk006 RSPO1) was developed during a project co-funded by Innovate UK. This protein replaces R-spondin conditioned media and mammalian-cell expressed R-spondin 1 to minimise batch variation and support scaling of organoid applications and is animal-derived component free. For samples or bulk pricing, please email us orders@qkine.com
High quality recombinant human Growth/differentiation factor 15 (GDF15) protein purified and refolded from E.coli. No contamination from related TGF beta family proteins, which solves a huge problem for researchers in this field (Olsen,2017). Tested in a well-characterised SMAD2/3 activation assay to confirm no SMAD signalling.
Please order online (where you can upload a PO), email orders@qkine.com or phone +44 (0) 1223 491486 / USA toll free 1-866 877 2185.
Our team are always happy to help and if you need reserved stock from batches you have validated, bulk orders or any further information, please contact us by phone or email (orders@qkine.com)
Well we don’t actually deliver everywhere by bike – unless you are in the middle of Cambridge, UK! We do ship for free to all US and European labs and biotechs. Please email orders@qkine.com if you are outside this area and we’ll let you know shipping costs (always reasonable).
We use proprietary refolding technologies and protein purification techniques developed at the University of Cambridge to produce high purity, animal-derived component free growth factors and cytokines in E.coli. By solving scientific challenges such as structural heterogeneity, poor stability and solubility and spurious interactions with other biomolecules,we provide you more reliable tools for stem cell and organoid culture.