Species matched growth factors for cellular agriculture including cultivated meat, fish, fat and dairy
Food Standards Agencies from around the world have continued support of alternative proteins and food innovation. In-depth reviews of current novel food frameworks, updating dossier submission platforms and updating food guidelines have resulted in further promise in this field.
With feedback from this progression and new guidelines from the FDA (Food and Drug Administration) in the US and UK Food Standards Agency (FSA), it is clear cultivated meat companies are being strongly advised to use growth factors with protein sequences that are 100% homologous to the species of animal they are cultivating in the production process. Growth factors from the target species also aid consumer acceptance and species-specific activity as well as regulatory considerations.
Qkine is dedicated to supporting the cellular agriculture industry by manufacturing high-purity and bioactive growth factors that are species-specific to cultivated cultures including porcine, bovine and fish.
Frequently used growth factors where the amino acid sequence is 100% conserved between human, bovine, and porcine species
Code | Product name | Species | Human to porcine | Human to bovine | Comments |
---|---|---|---|---|---|
Qk001 | Activin A | Human | 100% | 100% | Human sequence identical to porcine and bovine activin A |
Qk047 | IGF-1 | Human | 100% | 100% | Human sequence identical to porcine and bovine IGF-1 |
Qk045 | NRG-1 | Human | 100% | 100% | Human sequence identical to porcine and bovine NRG-1 |
Qk010 | TGF-β1 PLUS | Human | 100% | 100% | Human sequence identical to porcine and bovine TGF-β1 |
Qk072 | TGF-β2 | Human | 100% | 100% | Human sequence identical to porcine and bovine TGF-β2 |
Frequently used growth factors where the amino acid sequence is similar but not 100% conserved when comparing human, bovine and porcine species
Code | Product name | Species | Human to porcine | Human to bovine | Comments |
---|---|---|---|---|---|
Qk011 | EGF | Human | ~85% | – | Porcine EGF available (Qk064-FG) Bovine EGF coming soon (enquire for more information) |
Qk025 | FGF-2 (145 aa) | Human | ~99% | ~99% | Bovine/porcine FGF-2 (145 aa) available (Qk040-FG) |
Qk027 | FGF-2 (154 aa) | Human | ~99% | ~99% | Bovine/porcine FGF-2 (154 aa) available (Qk056-FG) |
Qk013 | HGF (NK1) | Human | ~95% | ~93% | Porcine HGF (NK1) available (Qk061-FG) Bovine HGF (NK1) available (Qk060-FG) |
Qk036 | LIF | Human | 87% | 88% | Porcine and bovine LIF coming soon |
Qk044 | PDGF-BB | Human | ~95% | 91% | Bovine PDGF-BB (Qk079-FG) Porcine PDGF-BB coming soon |
Qk054 | TGF-β3 | Human | ~98% | ~99% | Porcine TGF-β3 available (Qk084-FG) Bovine TGF-β3 coming soon |