SB431542 (Qk1103)

Product: Qk1103 Category:

Price range: £110.00 through £190.00

SB-431542 is an inhibitor of ALK5/TGF-β type I Receptor (IC50=94 nM) and is selective. SB 431542 also has inhibitory activity against ALK4 and ALK7 but not other proteins. SB 431542 can be used for induced differentiation of stem cells.

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Price range: £110.00 through £190.00

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Summary:

  • Cas No. 301836-41-9
  • Molecular Weight: 384.4
  • Storage: powder -20°C for 1 year, in solvent -80°C for 1 year

  • Solubility EtOH 3.85 mg/ml, DMSO 48.5 mg/ml

Featured applications:

  • Differentiation of iPSC into ectoderm

  • Neural differentiation from pluripotent stem cells

  • Differentiation of induced pluripotent stem cells to astrocytes

  • Differentiation of midbrain dopaminergic neurons

Alternative names
Species reactivity

Further quality assays

  • >99% purity

  • HPLC/HNMR: Consistent with structure

We are a company founded and run by scientists to provide a service and support innovation in stem cell biology and regenerative medicine.  All our products are exceptionally high purity, with complete characterisation and bioactivity analysis on every lot.

Preparation of SB431542 stock solution in DMSO/EtOH

1 mg5 mg10 mg
1 mM2.60 ml13.01 ml26.02 ml
5 mM0.52 ml2.60 ml5.20 ml
10 mM0.26 ml1.30 ml2.60 ml
Background references

Additional resources

    Our products are for research use only and not for diagnostic or therapeutic use. Products are not for resale.

    For use in manufacturing of cellular or gene therapy products. Not intended for in vivo applications.

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