Y-27632 dihydrochloride (Qk1104)

Product: Qk1104 Category:

Price range: £75.00 through £100.00

Y-27632 dihydrochloride (Y-27632 2HCl) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II. Y-27632 dihydrochloride also inhibits isolation-induced apoptosis in mouse prostate stem or progenitor cells.

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Price range: £75.00 through £100.00

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Summary:

  • Cas No. 129830-38-2
  • Molecular Weight: 320.26
  • Chemical name: 4-[(1R)-1-aminoethyl]-N-4-pyridinyl-trans-cyclohexanecarboxamide, dihydrochloride

  • Formula: C14H21N3O·2HCl

  • Storage: powder -20°C for 1 year, in solvent -80°C for 1 year

  • Solubility in DMSO 255 mg/ml, water 32 mg/ml

Featured applications:

  • Induced pluripotent stem cell culture and maintenance

  • Differentiation of iPSC into endoderm, mesoderm and ectoderm

  • Differentiation of midbrain dopaminergic neurons

  • Stem cell differentiation into neural and microglial lineages

  • Differentiation of induced pluripotent stem cells to astrocytes

Alternative names
Species reactivity

Further quality assays

  • >99% purity

  • HPLC/HNMR: Consistent with structure

We are a company founded and run by scientists to provide a service and support innovation in stem cell biology and regenerative medicine.  All our products are exceptionally high purity, with complete characterisation and bioactivity analysis on every lot.

Preparation of Y-27632 dihydrochloride stock solution in DMSO/H2O

1 mg5 mg10 mg
1 mM3.12 ml15.61 ml31.22 ml
5 mM0.62 ml3.12 ml6.24 ml
10 mM0.31 ml1.56 ml3.12 ml
20 mM0.16 ml0.78 ml1.56 ml
Background references

Additional resources

    Our products are for research use only and not for diagnostic or therapeutic use. Products are not for resale.

    For use in manufacturing of cellular or gene therapy products. Not intended for in vivo applications.

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