Technote | SB431542 (Qk1103)
Qkine small molecule SB431542 can be used for neuroectoderm differentiation from iPSC
Differentiating iPSCs into ectoderm linage of cells provides unparalleled potential for disease modeling, drug discovery, and cell-based therapies, all without the ethical concerns associated with using embryonic stem cells. The ectoderm has a role in generating a wide range of vital tissues and organs, including central and peripheral nervous systems, sensory organs, and skin.
Qkine small molecules are highly pure and validated in differentiation protocols to ensure maximum confidence for your stem cell workflow.
Differentiation of iPSC into ectoderm

Immunocytochemistry of neuroectoderm markers in differentiated iPSCs. SRY-box transcription factor 1 (SOX1) [Green, A], Hoechst33258 [Blue, B], combined SOX1 and Hoechst [C] and SRY-box transcription factor 2 (SOX2) [Green, D], Hoechst33258 [Blue, E], combinedSOX2 and Hoechst [F]. Images were acquired using the EVOS M5000 system.
Qkine recombinant proteins and small molecules have the advantage of being highly pure and animal origin-free, giving lot-to-lot consistency in activity for reproducible differentiation of stem cells and organoids.
All our recombinant proteins are animal-free and come with Bioactivity. Guaranteed.
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Qkine is committed to manufacturing bioactive proteins of the highest quality to enhance scientific outcomes and improve reproducibility.

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Animal-free
Qkine manufactures recombinant proteins in a dedicated animal-free laboratory located in an ISO 9001: 2015 certified facility.
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