Complete animal-free hepatocyte differentiation process
The complete set of fully animal-free growth factors for the differentiation of human pluripotent cells to hepatocytes is available. To ensure reproducibility of your endoderm differentiation protocols every lot is thoroughly tested for biochemical purity and bioactivity. Lot-specific quality control data and animal origin-free (AOF/ADCF) certificates are available to facilitate planning for the transition to pre-clinical studies and establishing future GMP-compliant processes.
Product focus
Enhanced hepatocyte differentiation using HGF natural isoform NK1
The NK1 isoform is the smallest naturally occurring splice variant of HGF, it comprises the HGF N-terminal and first kringle domain. This isoform promotes efficient differentiation of human iPSCs to hepatocyte-like cells at just 10 ng/ml, resulting in highly homogeneous expression of the hepatic marker, HNF4α. Qkine HGF NK1 is also completely animal-free (AOF), making it suitable for chemically defined media and reproducible scale-up.
