Recombinant human Activin A Plus protein is a high purity, animal-free 24 kDa biologically active truncation of the mature domain of human Activin A protein. Our recombinant Activin A PLUS is designed to be manufactured at scale for cost-effective large-scale stem cell culture applications. 

Recombinant human Gremlin 1 protein has been optimized by our experts for exceptionally high-purity production and bioactivity.   Gremlin-1 is a BMP-inhibitor present in the natural intestinal niche and provides an animal-free substitute for Noggin in chemically-defined media for many ESC, iPSC and organoid culture systems. 

Recombinant human HGF (NK1) protein is a high purity NK1 isoform of human hepatocyte growth factor (HGF) that promotes efficient differentiation of human iPSCs to hepatocyte-like cells at just 10 ng/ml with highly homogeneous expression of the hepatic marker, HNF4α.  The highly scalable animal-free manufacture and enhanced bioactivity make this suitable for chemically-defined media and reproducible scale-up.

Recombinant human R-spondin 1 protein (RSPO1) is a 13kDa highly pure, bioactive fragment of human R-spondin 1. Our recombinant human R-spondin 1 protein is animal-free and not glycosylated to ensure production of homogeneous protein and enhanced comparability between batches.

Recombinant human R-spondin 3 protein is a 17 kDa bioactive fragment of human R-spondin 3 protein comprised of the two cysteine-rich furin-like domains, which are essential for its activity in stem cell and organoid culture. Our recombinant R-spondin 3 has been purified to homogeneity and is animal-free to ensure batch to batch consistency when adding to chemically-defined culture media.

Recombinant human TGF-β1 PLUS protein is the first entirely animal-free recombinant human transforming growth factor beta 1 (TGF-β1) protein for highly reproducible results and compatible with chemically-defined stem cell media. Our  TGF-β1 PLUS protein has been extensively tested for maintenance of iPSC pluripotency by the specialist stem cell biotechnology company, Stemnovate, Cambridge, UK.

*Benchmark our TGF-β1 PLUS against your existing supplier*