Class of 2024: Qkine released 25 new products plus 24 food grade products in 2024!
January
2024 started very strong with the launch of IL-1ß as part of our mesenchymal stem cell range. TGF-ß2 to complete our TGF-beta family and DKK-1, the first commercially available bioactive animal origin-free recombinant DKK-1.
Recombinant human IL-1β protein (Qk101)
IL-1β is used to stimulate and activate immune cells (macrophages and T cells), maintain hematopoietic progenitor cells, and modulate the differentiation of mesenchymal stem cells.
Recombinant human TGF-β2 protein (Qk072)
Transforming Growth Factor beta 2 (TGF-β2), part of the TGF-β superfamily, regulates a wide array of cellular processes, including proliferation, differentiation, wound healing, apoptosis, metabolism, embryogenesis, and tissue repair. It is an essential growth factor in many embryonic and induced pluripotent stem cell culture media.
February
February saw the launch of two new hematopoietic stem cell proteins, interleukins, IL-4 and IL-6.
Recombinant human IL-4 (Qk092)
IL-4 plays a crucial role in hematopoiesis, the regulation of antibody production, the stimulation of activated B cell and T cell proliferation, and the differentiation of B cells into plasma cells.
Recombinant human IL-6 (Qk093)
IL-6 is suitable for the culture of reproducible and high-quality hematopoietic stem cells and other relevant cells.
March
In our commitment to supply species-matched growth factors, in March Qkine launched mouse EGF, bovine/porcine FGF2-G3 and salmon FGF-2. FGF2-G3 is a thermostable modification of FGF-2 and was launched in the 154 aa and shorter more bioactive 145 aa versions. We also further expanded our hematopoietic stem cell range with TNF-alpha.
Recombinant mouse EGF Protein (Qk066)
Mouse EGF is crucial for stem cell maintenance, proliferation, differentiation, organoid culture growth and survival. It is also widely used for disease modelling, drug screening, tissue engineering, and regenerative medicine. Overall, EGF is a key player in cellular regulation and functions.
Recombinant human TNF-alpha protein (Qk083)
Tumor necrosis factor-alpha (TNF-α) is a cytokine involved in cell signaling, primarily produced by immune cells like macrophages. It plays a central role in inflammation, immunity, and regulating cell survival and death. Qkine TNF-α is suitable for the culture of reproducible and high-quality hematopoietic stem cells and other relevant cells.
Recombinant bovine/porcine FGF2-G3 (145 aa) protein (Qk080)
Bovine FGF2-G3 is used for the development of optimized serum-free culture media for species-specific bovine (cow) and porcine (pork) cultivated meat and veterinary research applications, including the expansion of bovine and porcine smooth muscle cells, bovine and porcine induced pluripotent, embryonic and mesenchymal stem cells.
Recombinant bovine/porcine FGF2-G3 (154 aa) protein (Qk081)
Bovine FGF2-G3 is used for the development of optimized serum-free culture media for species-specific bovine (cow) and porcine (pork) cultivated meat and veterinary research applications, including the expansion of bovine and porcine smooth muscle cells, bovine and porcine induced pluripotent, embryonic and mesenchymal stem cells.
Recombinant salmon FGF-2 (145 aa) protein (Qk102)
Recombinant salmon FGF-2 protein 145 aa (bFGF/basic FGF) for the development of optimized serum-free culture media for species-specific Atlantic salmon (Salmo salar) in cellular agriculture protocols and veterinary research applications.
Recombinant salmon FGF-2 (154 aa) protein (Qk103)
Recombinant salmon FGF-2 protein 145 aa (bFGF/basic FGF) for the development of optimized serum-free culture media for species-specific Atlantic salmon (Salmo salar) in cellular agriculture protocols and veterinary research applications.
April
April saw the launch of porcine TGF-ß3 to support cellular agriculture applications and human SCF, another key hematopoietic stem cell growth factor.
Recombinant porcine TGF-β3 protein (Qk084)
Porcine TGF-β3 is used in cultivated meat pluripotent stem cell maintenance medias, such as Beefy9 media.
Recombinant human SCF protein (Qk078)
Stem cell factor (SCF) is a critical factor in the maintenance and expansion of hematopoietic stem cells (HSCs) in the bone marrow microenvironment. Key myeloid progenitor differentiation factor for a variety of myeloid cells such as megakaryocytes, basophils, neutrophils, and monocytes, SCF is also a primary growth and activation factor for mast cells and eosinophils.
May
The FGF family was the focus in May, with the launch of FGF-18, a key osteogenic differentiation factor and to join salmon FGF-2 for cultivated fish, tuna FGF-2 154 aa and 145 aa.
Recombinant human FGF-18 protein (Qk069)
FGF-18 is widely used to support cell culture maintenance and proliferation, promote chondrogenic and osteogenic differentiation of stem cells, stimulate angiogenesis, and enhance tissue regeneration.
Recombinant tuna FGF-2 (145 aa) protein (Qk104)
Recombinant tuna FGF-2 protein 154 aa (bFGF/basic FGF) for the development of optimized serum-free culture media for species-specific yellowfin tuna (Thunnus albacares) in cellular agriculture protocols and veterinary research applications.
Recombinant tuna FGF-2 (154 aa) protein (Qk105)
Recombinant tuna FGF-2 protein 145 aa (bFGF/basic FGF) for the development of optimized serum-free culture media for species-specific yellowfin tuna (Thunnus albacares) in cellular agriculture protocols and veterinary research applications.
June
Recombinant eel FGF-2 (145 aa) protein (Qk106)
Eel FGF-2 protein 145 aa (bFGF/basic FGF) for the development of optimized serum-free culture media for species-specific European (Anguilla anguilla), Japanese (Anguilla japonica) and American (Anguilla rostrata) eel in cellular agriculture protocols and veterinary research applications.
Recombinant eel FGF-2 (154 aa) protein (Qk107)
Eel FGF-2 protein 154 aa (bFGF/basic FGF) for the development of optimized serum-free culture media for species-specific European (Anguilla anguilla), Japanese (Anguilla japonica) and American (Anguilla rostrata) eel in cellular agriculture protocols and veterinary research applications.
July
July was an exciting month, Qkine launched its first extracellular matrix protein, human vitronectin which was validated for use in iPSC maintenance in our weekend-free protocol.
Recombinant bovine PDGF-BB protein (Qk079)
Bovine PDGF-BB (platelet-derived growth factor BB) protein is a homodimer of PDGF-B peptide chains. PDGF-BB can be used for the development of optimized serum-free culture media for species-specific bovine in cellular agriculture protocols. PDGF-BB can be added to bovine culture medium to promote rapid and efficient cell division, maintain high cell proliferation rates in bioreactors, promote the maturation of bovine myoblasts into myotubes and stimulate the production of extracellular matrix components.
August
In August we launched IL-7 to join our hematopoietic stem cell range and our high quality food grade proteins. Qkine has close links to the cellular agriculture sector and supports both academic and industrial partners. To this end our high quality food grade products are manufactured under a HACCP regime, with all the extra documentation needed for regulatory dossier completion. This includes allergen statements, CoO, CoA, beta lactam etc. read more about our food grade protein manufacturing processes and documentation.
Recombinant human IL-7 protein (Qk095)
Interleukin-7 (IL-7) is a vital cytokine essential for immune system regulation, particularly in the development and maintenance of T cells, playing a crucial role in both adaptive and innate immune responses. Recombinant human IL-7 stimulates the development of lymphoid progenitor cells.
Food Grade Products
Recombinant bovine/porcine FGF-2 (145 aa) protein (Qk040-FG)
Recombinant bovine/porcine FGF-2 (154 aa) protein (Qk056-FG)
Recombinant bovine HGF NK1 protein (Qk060-FG)
Recombinant porcine HGF NK1 protein (Qk061-FG)
Recombinant porcine EGF protein (Qk064-FG)
Recombinant bovine PDGF-BB protein (Qk079-FG)
Recombinant bovine/porcine FGF2-G3 (145 aa) protein (Qk080-FG)
Recombinant bovine/porcine FGF2-G3 (154 aa) protein (Qk081-FG)
Recombinant porcine TGF-β3 protein (Qk084-FG)
Recombinant salmon FGF-2 (145 aa) protein (Qk102-FG)
Recombinant salmon FGF-2 (154 aa) protein (Qk103-FG)
Recombinant tuna FGF-2 (145 aa) protein (Qk104-FG)
Recombinant tuna FGF-2 (154 aa) protein (Qk105-FG)
Recombinant eel FGF-2 (145 aa) protein (Qk106-FG)
Recombinant eel FGF-2 (154 aa) protein (Qk107-FG)
Recombinant bovine/porcine activin A protein (Qk108-FG)
Recombinant bovine/porcine activin A PLUS protein (Qk109-FG)
Recombinant bovine/porcine FRACTA protein (Qk110-FG)
Recombinant bovine/porcine TGF-β1 PLUS protein (Qk111-FG)
Recombinant bovine/porcine TGF-β2 protein (Qk112-FG)
Recombinant bovine/porcine IGF-1 protein (Qk113-FG)
Recombinant bovine/porcine IGF-1 LR3 protein (Qk114-FG)
Recombinant bovine/porcine NRG-1 protein (Qk115-FG)
Recombinant zebrafish FGF2 protein (Qk116-FG)
September
September saw the launch of activin E PLUS, the only commercially available bioactive activin E recombinant protein. Human IL-2 recombinant protein was also launched, optimized for high bioactivity.
Recombinant human activin E PLUS protein (Qk067)
Human recombinant activin E PLUS protein is an optimised biologically active truncation of the mature domain of human activin E protein, of significant interest for drug discovery across various fields.
Recombinant human IL-2 protein (Qk089)
Interleukin-2 (IL-2) is a vital cytokine that regulates immune responses by promoting the growth and activation of T-cells, enhancing immune function, and maintaining immune tolerance for immune activation and suppression.
October
In October, IGF-2 another osteogenic stem cell differentiation factor and IFN-gamma another hematopoietic stem cell factor were launched.
Recombinant human IGF-2 protein (Qk118)
Insulin-like Growth Factor 2 (IGF-2) is a growth factor that promotes cell proliferation, differentiation, and survival, particularly during fetal development. IGF-2 also regulates tissue growth and muscle regeneration.
Recombinant IFN-gamma protein (Qk117)
IFN-gamma (interferon-gamma) is a cytokine crucial for immune responses, produced by T cells and natural killer cells. It activates macrophages, enhances antigen presentation, and plays a key role in inflammation.
December
As the year draws to a close, we look forward to the launch of mouse SCF and human IL-15, to keep track of these and future releases see our coming soon, subscribe to our newsletter (at the bottom of this page) and follow us on LinkedIn.
Well done team!
All our growth factors are manufactured within a stringent quality framework, ensuring high-quality proteins that maintain robust, reproducible, and physiologically relevant stem cell and organoid cultures that adhere to our Nine-point Quality Commitment.
