From standardization of imaging techniques, to more reproducible and cost-effective organoid culture media Organoids have the potential to revolutionize current drug discovery approaches, enhance the physiological relevance of in vitro disease models, and deliver on the promise of precision medicine. But, as with any new technology, there are a number of hurdles to overcome as [...]
Most industries today are under pressure to switch to more ethical and sustainable animal-free alternatives, and now the trend is coming to stem cell labs. As stem cell applications accelerate towards the clinic, novel drug discovery platforms are rapidly scaled, and new transformative stem cell-based technologies such as cultured meat arise, there is [...]
Cambridge, UK 21 July 2020: Qkine – a specialist developer and manufacturer of proteins for stem cell, organoid and regenerative medicine applications – is delighted to announce the appointment of Rob Nixon to its management team as Head of Commercial and Dr Cassie Doherty, Investment Director at Parkwalk, to its board. With years of [...]
Presentation by Luana Ferrara, Senior Protein Scientist Video script Slide 1: Introduction Hello! My name is Luana Ferrara and I am a senior protein scientist at Qkine. In this short video, I’ll be presenting a comparative analysis of the purity of recombinant Activin A from different suppliers and highlighting why it's important to consider the biochemical quality of growth factors for your stem cell culture. Slide 2: The role of [...]
Cambridge, UK 08 June 2020: Qkine – a specialist developer and manufacturer of proteins for stem cell, organoid and regenerative medicine applications – today announced the successful closure of a £1.5M series A investment round to accelerate the global scale-up of its commercial operations and make key hires to its leadership team. The funding [...]
Hydrophobic or aromatic? Flexible or rigid? We've designed a handy (and free!) infographic of the amino acid chemical structures and side chain properties. Why not save a copy and hang it up in your lab?
Qkine secures additional £550K to extend development of R&D pipeline and accelerate commercialisation of product portfolio
Cambridge, UK 03 June 2019: Qkine, specialist manufacturer of proteins for stem cell, organoid and regenerative medicine applications, has closed a further round of investment. The £550K funding round was led by Cambridge Enterprise and five angel investors – all of whom followed initial seed investments made in April 2018. Joining the original investors [...]
As a structural biologist, one will very quickly realise that protein not only needs to be pure, but it needs to be also homogeneous and the real proof of the protein’s quality is in its specific bioactivity. So,we clearly need different criteria for defining quality and that is what we do at Qkine.
Running for over a decade, the iteams programme partners multi-disciplinary teams of PhD students and postdocs with inventors from the University of Cambridge. As we are a recent spin-out from the academic laboratory of our scientific founder Marko Hyvonen, we have had the pleasure of working with an iteam over the last months. The [...]
Building next generation growth factors for organoid-driven precision medicine: a protein engineering project co-funded by Innovate UK
We were delighted to be awarded Innovate UK funding to address issues of quality and availability of growth factors for use in organoid technologies. The Qkine R&D team are applying a combination of protein expression, refolding optimisation and structure-guided protein engineering to improve the biological properties and quality of proteins such as R-spondins, TGFβ1, members of the BMP and FGF family proteins.