30 07, 2024

Pep Talk July 2024

2024-07-30T12:21:46+00:00July 30th, 2024|newsletter, Resources|

In this edition, we are excited to announce our complete transition to animal origin-free (AOF) manufacturing for all recombinant proteins. This ensures the highest quality and consistency for researchers relying on these critical components. Additionally, discover our latest application notes featuring AOF BDNF and GDNF for neural differentiation and thermostable FGF-2 and TGF-β1 for weekend-free iPSC culture.

24 07, 2024

ISSCR 2024 reflections on “Standards for Human Stem Cell Use in Research” and growth factors for cell therapy manufacture

2024-07-25T16:45:56+00:00July 24th, 2024|animal-free, Blog, News, protein science, quality, Resources, stem cells|

Reflections on the dynamic ISSCR 2024 workshop on Standards for Human Stem Cell Use in Research including recommendations for growth factor supply chains for raw (ancillary materials) for cell therapy and ATMP manufacture.

24 07, 2024

The Cautionary Tale of GDF-15

2024-07-25T06:11:35+00:00July 24th, 2024|animal-free, Blog, News, protein science, quality, Resources|

Commercial sources of recombinant human GDF15 protein, in particular those purified from mammalian expression, are frequently contaminated with trace amounts of TGFβ and related proteins. These trace contaminants cause misleading experimental results due to the picomolar or even femtomolar EC50s of this family of cytokines.  Please be cautious with your source of recombinant GDF15 protein.

9 07, 2024

Qkine and StemCultures collaborate to provide new solutions for precision stem cell culture

2024-07-09T16:09:20+00:00July 9th, 2024|animal-free, Blog, News, Press Release, protein engineering, protein science, quality, Resources, stem cells|

Specialist bioactive growth factor protein manufacturer Qkine today announced a new partnership with StemCultures, a life sciences company dedicated to developing innovative reagents that enhance the quality and efficiency of cell growth and differentiation in culture.

20 06, 2024

Selection of growth factors and cytokines source for the manufacture of cell therapies, tissue-engineered products and translational stem cell research applications

2024-06-20T07:54:39+00:00June 20th, 2024|animal-free, Blog, News, Resources|

The manufacture of cell and gene therapy products and tissue-engineered regenerative medicine products often requires recombinant proteins such as growth factors and cytokines. These are classified as raw or ancillary materials ie. culture media components or reagents that are not intended to be included in the final product.

13 06, 2024

Pep Talk June 2024

2024-06-13T09:37:44+00:00June 13th, 2024|newsletter, Resources|

In this edition, we are excited to announce our complete transition to animal origin-free (AOF) manufacturing for all recombinant proteins. This ensures the highest quality and consistency for researchers relying on these critical components. Additionally, discover our latest application notes featuring AOF BDNF and GDNF for neural differentiation and thermostable FGF-2 and TGF-β1 for weekend-free iPSC culture.

5 06, 2024

Transitioning to a fully animal origin-free recombinant protein manufacturing process

2024-06-10T12:23:43+00:00June 5th, 2024|animal-free, Blog, News, Resources|

We've recently fully transitioned to an animal origin-free (AOF) manufacturing process for our recombinant proteins. This shift ensures the highest standards of safety, purity, and sustainability in bioproduction. By eliminating all animal-derived components, including heparin-based purification columns, we’re supporting ethical and cruelty-free biomanufacturing. Learn more about our journey to 100% AOF.

9 01, 2024

Nurturing Complexity: The role of vascularization in Organoid Advancements

2024-01-09T11:27:37+00:00January 9th, 2024|Blog, organoid news|

Organoids are exciting models that are rapidly becoming a hopeful platform for many medical advances such as drug screening and disease modeling. However, due to a lack of vascularization, they have limitations for future applications. This review blog summarizes several practical methods for successful organoid vascularization to date.

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