Technote | CHIR99021 and LY294002 (Qk1101Qk1102)
Qkine small molecules CHIR99021 and LY294002 can be used for mesoderm differentiation from iPSC
Differentiating iPSCs into mesoderm lineage of cells provides unparalleled potential for disease modeling, drug discovery, and cell-based therapies, all without the ethical concerns associated with using embryonic stem cells. The mesoderm has a role in generating a wide range of vital tissues and organs, including the heart, blood, muscles, and bones.
Qkine small molecules are highly pure and validated in differentiation protocols to ensure maximum confidence for your stem cell workflow.
Differentiation of iPSC into mesoderm
Immunocytochemistry of Mesoderm markers in differentiated iPSCs. Transcription factor Brachyury [Green, A], Hoechst 33258 [Blue, B],combined Brachyury and Hoechst [C] and transcription factor MIXL1 [Green, D], Hoechst33258 [Blue, E], combined MIXL1 and Hoechst [F]. Images were acquired using the EVOS M5000 (scale bar = 300 µm).
Qkine recombinant proteins and small molecules have the advantage of being highly pure and animal origin-free, giving lot-to-lot consistency in activity for reproducible differentiation of stem cells and organoids.
All our recombinant proteins are animal-free and come with Bioactivity. Guaranteed.
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