Quality commitment 9
From concept to manufacture, our proteins are designed to be the best
At Qkine every aspect of protein design and manufacture is considered to ensure you get the best protein for your research
Engineered for improved stability in cell culture
Recombinant FGF2-G3 (FGF2-STAB®) protein is a thermostable engineered form of FGF-2 (bFGF). Qk053 is the 154 aa mature domain of FGF-2 (Qk027) with nine amino acid substitutions to enhance stability without impacting bioactivity. This increases the functional half-life of the protein from <10 h (wild-type) to >7 days (FGF2-G3).
Proteins modified to enhance biological activity
Follistatin-resistant activin A (FRACTA) protein has been engineered to prevent binding to the natural inhibitor, follistatin. Activin A activity protein is regulated in vivo by follistatin, a high-affinity inhibitor; follistatin accumulates in stem cell culture, where it inhibits activin A.
Qk035 follistatin-resistant activin A (FRACTA) has equivalent bioactivity to wild-type activin A
(Qk001) but does not bind follistatin so is resistant to feedback inhibition.
Animal-origin free manufacturing of complex proteins
Transforming growth factor beta-1 (TGF-β1) is a common component of human pluripotency maintenance media. However, as TGF-β1 is a highly complex protein, it is difficult to manufacture in microbial expression systems.
Qkine TGF-β1 PLUS (Qk010) is the world’s first animal origin-free TGF-β1, manufactured for highly reproducible results.
Getting the simple things right is important.
At Qkine, we are committed to raising the standard in bioactive protein manufacturing.
Our science team is here to help, please contact us if you have any questions at customerservice@qkine.com.
Protein production
The final form of all our proteins are completely
Tag-free
Carrier-free
to remove scientific uncertainty and ensure compatibility with translational studies.
Quality in every aspect
For total confidence quality is designed into every aspect of protein development and manufacturing
Higher-compliance quality assurance, manufactured in our ISO 9001:2015 certified facility
Quality control, ever lot tested for bioactivity, purity and sterility
Regulatory documentation available on request
Raising the standard in bioactive protein manufacturing and innovation
Our science team is here to help, please contact us if you have any questions.