Quality commitment 9

From concept to manufacture, our proteins are designed to be the best

At Qkine every aspect of protein design and manufacture is considered to ensure you get the best protein for your research

Protein engineering

We use protein engineering to enhance specific protein properties and address scientific challenges

Engineered for improved stability in cell culture

Recombinant FGF2-G3 (FGF2-STAB®) protein is a thermostable engineered form of FGF-2 (bFGF). Qk053 is the 154 aa mature domain of FGF-2 (Qk027) with nine amino acid substitutions to enhance stability without impacting bioactivity. This increases the functional half-life of the protein from <10 h (wild-type) to >7 days (FGF2-G3).

Proteins modified to enhance biological activity

Follistatin-resistant activin A (FRACTA) protein has been engineered to prevent binding to the natural inhibitor, follistatin. Activin A activity protein is regulated in vivo by follistatin, a high-affinity inhibitor; follistatin accumulates in stem cell culture, where it inhibits activin A.

Qk035 follistatin-resistant activin A (FRACTA) has equivalent bioactivity to wild-type activin A (Qk001) but does not bind follistatin so is resistant to feedback inhibition.

Follistatin is a natural inhibitor of Activin A

Animal-origin free manufacturing of complex proteins

Transforming growth factor beta-1 (TGF-β1) is a common component of human pluripotency maintenance media. However, as TGF-β1 is a highly complex protein, it is difficult to manufacture in microbial expression systems.

Qkine TGF-β1 PLUS (Qk010) is the world’s first animal origin-free TGF-β1, manufactured for highly reproducible results.

Getting the simple things right is important.
At Qkine, we are committed to raising the standard in bioactive protein manufacturing.
Our science team is here to help, please contact us if you have any questions at customerservice@qkine.com.

Protein production

The final form of all our proteins are completely

to remove scientific uncertainty and ensure compatibility with translational studies.

Quality in every aspect

For total confidence quality is designed into every aspect of protein development and manufacturing

Discover our reliable growth factors & cytokines
to improve reproducibility in your stem cell cultures

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Animal-free

Protein purification is critical for growth factor purity

Qkine manufactures recombinant proteins in a dedicated animal-free laboratory. Our manufacturing process ensures every stage is controlled to provide an animal-free product.

ISO 9001 QMS certification

Qkine ISO 9001: 2015 certification

Qkine is an ISO 9001:2015 certified company. Learn more about our quality management system which has been implemented to comply with the requirements of ISO 9001:2015.

Quality control

Animal origin-free proteins quality control

To ensure results are reliable and reproducible every time, we have stringent quality control procedures in place to provide highly pure proteins with exceptional bioactivity.

Contact our expert team

Our dedicated team of stem cell specialists is available to answer any queries and to give expert support when required.

Raising the standard in bioactive protein manufacturing and innovation

Our science team is here to help, please contact us if you have any questions.