Technote | Activin A (Qk001)
Qkine activin A can be used to create functionally differentiated retinal pigmented epithelium (RPE)
The retinal pigment epithelium (RPE) is a polarized monolayer of cells that provides essential functions to the light-sensitive photoreceptors in the retina. Differentiation of induced pluripotent stem cells into functionally relevant RPE cells provides a model for the study of RPE function and disease mechanisms.
Qkine activin A (Qk001) is a high-purity mature bioactive dimer which is animal origin-free, carrier protein-free and tag-free.
Differentiated RPE using Qkine activin A
(A) Light microscope image of a retinal pigmented epithelium (RPE) monolayer differentiated from hiPSC using Qkine human activin A (Qk001) (B) Stained with DAPI (blue) and RPE markers ZO1 (green) and BEST1 (red).
Images provided by Srishti Silvano and Cerys Manning, University of Manchester
Qkine recombinant proteins have the advantage of being highly pure and animal origin-free, giving lot-to-lot consistency in bioactivity for long-term reproducible differentiation of stem cells and organoids.
All our recombinant proteins are animal-free and come with Bioactivity. Guaranteed.
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