Technote | BMP-4 (Qk038)

Qkine bone morphogenetic protein 4 (BMP-4) protein produces consistently high bioactivity lot-to-lot

Human bone morphogenetic protein 4 (BMP-4) is a key regulator of embryogenesis and supports the differentiation of induced pluripotent stem cells (iPSC) and embryonic stem cells (ECS). BMP-4 plays a role in bone and cartilage formation, tissue repair, and organ and neuronal development.

BMP-4 is part of the TGF-β superfamily and has a complex biochemical structure, expertise is required to manufacture bioactive BMP-4. Qkine BMP-4 (Qk038) has exceptional lot-to-lot consistency.

Qkine BMP-4 lot validation

  • Four independent lots of BMP-4 (Qk038) were tested using a BMP-4 responsive firefly luciferase reporter assay.
  • Qkine recombinant human BMP-4 lots show a narrow bioactivity range across the four batches of 17-34 pM.
Lot EC50 (pM)
#104296 33.1
#104329 18.3
#104357 17.2
#104357 29.0

Qkine BMP-4 (Qk038) is highly pure, bioactive and animal origin-free. Qkine tests all newly manufactured lots against previous lots ensuring exceptional lot-to-lot consistency and allowing increased reproducibility for stem cell culture and differentiation.

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All our recombinant proteins are animal-free and come with Bioactivity. Guaranteed.

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Qkine is committed to manufacturing bioactive proteins of the highest quality to enhance scientific outcomes and improve reproducibility.

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Qkine manufactures recombinant proteins in a dedicated animal-free laboratory located in an ISO 9001: 2015 certified facility.

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