Qkine and WildBio collaborate to progress cultivated meat production from wild game species
For the cultivated meat industry, the goal is to produce a quality raw material quickly and at a reduced cost. At WildBio, we are harnessing the power of cells from wild game species in South Africa.
Cells derived from the Sable Antelope, a Bovidae family member native to South Africa, were cultured using growth factors from Qkine. We were able to generate harvestable, quality mass in just six days (as compared to the 2-6 week timeframe for adherent tissue formation), far faster than previously described methods for generating cultivated meat. We are unlocking the power of cell types not currently being used in the industry to generate meat and, with the help of the growth factors from Qkine, we are achieving that goal at a rapid pace.
“I am so grateful for the collaboration with Qkine. We are surprising ourselves in what is possible for cellular agriculture and the research community at large using Qkine’s vast array of growth factors with cell lines from wild game.” Jill, WildBio consulting CSO
We are excited to share some of this data showing the effect of Qkine wild type bovine/porcine FGF-2 145 aa protein (Qk040) vs thermostable FGF2-G3 145 aa (Qk080) in the culture of sable bone marrow cells. We also share interesting preliminary data showing improved cell mass gain through using Qkine TGF-ß1 (Qk010) and TGF-ß2 (Qk072).
“The team at Wild Bio have developed an impressive array of cell lines from a fascinating range of South African native species. This will help the field understand the intricate cross-species drivers of cell mass creation and creates a unique resource for media optimization and growth factor selection. It’s an absolute delight to collaborate with their exceptional team, they are achieving impressive results at speed!” Catherine Elton, Qkine CEO
Sable bone marrow cells (Control)
Sable bone marrow cells + 100 ng/ml bovine/porcine FGF-2 145 aa (Qk040)
Sable bone marrow cells + 100 ng/ml FGF2-G3 145 aa (Qk080)
Sable bone marrow cell cultures benefited from the thermostability of FGF2-G3 (Qk080), both 145 aa FGF-2 forms are equally bioactive but the increased thermostability of FGF2-G3 increased cell proliferation.
Sable muscle cells (Control)
Sable muscle cells + 10 ng/ml TGF-ß2 (Qk072)
Sable muscle cells + 100 ng/ml TGF-ß2 (Qk072)
Sable muscle cells + 10 ng/ml TGF-ß1 (Qk010)
Sable muscle cells + 100 ng/ml TGF-ß1 (Qk010)
Qkine TGF-ß1 and TGF-ß2 allow the production of harvestable, quality mass in just six days. Sable muscle cells usually require 2-6 weeks to form adherent tissue which is difficult to harvest. However, the use of Qkine growth factors created harvestable tissue mass far faster than previously described methods for generating cultivated meat.
More about WildBio: www.wildbio.org
