Interleukin 3 (IL-3) is a hematopoietic growth factor that promotes the proliferation, growth, and survival of myeloid cells. Interleukin 3 is commonly used in cell culture to stimulate the differentiation and maturation of human-induced pluripotent stem cells towards myeloid progenitors such as mast cells, basophils, neutrophils, eosinophils, monocytes, and megakaryocytes.
Animal-free growth factors can ensure cell cultures are reproducible and physiologically relevant as they have higher lot-to-lot consistency and eliminate contamination from animal-derived ingredients. Qkine manufactures an animal-free, carrier-free, and tag-free Interleukin 3 to ensure high and consistent bioactivity. This technote demonstrates a comparable level of bioactivity to an alternative major supplier of interleukin 3.