Organoids are exciting models that are rapidly becoming a hopeful platform for many medical advances such as drug screening and disease modeling. However, due to a lack of vascularization, they have limitations for future applications. This review blog summarizes several practical methods for successful organoid vascularization to date.
Complex 3D liver models that more closely mimic human biology open opportunities for improved drug and vaccine discovery for malaria and related parasitic diseases.
Despite advances in research, around 90% of drugs fail during phase 1 clinical trials. New drugs for the treatment of cardiovascular disease and oncology have a particularly high failure rate, largely attributed to cardiotoxicity...
Can Super Scientist give you your organoid mojo back? Are your growth factors the reason your experiments fail? Can you use engineered or niche-specific growth factors to improve your organoid culture? Super Scientist flies in with easy fixes and questions to ask yourself - do you need to ditch the conditioned media, play around with growth factor combinations, switch noggin and gremlin, or be bold and explore new engineered proteins.
Qkine certified ISO9001: 2015 for its quality management system encompassing R&D, manufacturing, and operations in Cambridge, UK. Qkine supplies growth factors and cytokines to the fast-moving stem cell, organoid and emerging cultured meat sectors. Exceptional product quality and scientific support are crucial to customer's business processes and experimental outcomes.
Qkine, Manchester BIOGEL and Cellesce have been awarded Innovate UK Sustainable Innovation Funding to develop fully synthetic, chemically-defined three-dimensional (3D) scaffolds to enable manufacture scale up and improve reproducibility of patient-derived organoids.
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