Qk032: R-spondin-3 (human)

£100.00£1,600.00

R-Spondin-3 (RSPO3) protein is an essential component of Wnt 3a, R-spondin-3 (or 1,2), Noggin (WRN) media used widely in propagation of intestinal organoids and other stem cell and organoid models. Animal and carrier protein free.

Description

R-Spondin-3 (RSPO3) protein is an activator of the canonical Wnt signaling pathway.  In the colon, R-spondin 3 promotes stem cell recovery and epithelial repair via induction of Wnt.
Qkine R-spondin-3 protein is a highly defined, animal-free pure biologically active protein fragment comprising the two cysteine-rich, furin-like domains, which are necessary and sufficient for Wnt signal potentiation and are the essential domains for activity in organoid culture.  An R-spondin such as R-spondin-3 is an essential component of Wnt 3a, R-spondin-3 (or 1,2), Noggin (WRN) media used widely in propagation of intestinal organoids (2).

We produce R-spondin 1 in E.coli, so the protein is not glycosylated and is produced in animal-derived component free laboratory making it ideal for formulation of defined media. We provide bulk pricing and batch stock reservation for this protein.

Bioactive domain of human R-spondin-3, RSPO3 (residues 135-288, Uniprot: Q9BXY4) expressed in E.coli and purified to homogeneity.

Protein is provided lyophilize and carrier-protein free  Animal-derived component free.

Please visit our R-spondin-3 online datasheet for full details.

We take the quality of our products very seriously. All our proteins are produced in our Cambridge, UK, facility by our scientists and we provide comprehensive testing data for every batch.

Additional information

Unit size

1000 µg, 500 µg, 100 µg, 50 µg, 25 µg

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