Recombinant zebrafish FGF-2 / basic FGF (Qk002)

£250.00£400.00

Mature domain of zebrafish Danio rerio FGF2 (residues 2-154, Uniprot: B3DGE3) expressed in E.coli and purified to homogeneity as described in Ludwig et al. Nat. Methods 3, 637–646 (2006).

Protein is in PBS at 2-10 mg/ml (carrier protein-free)

SKU: Qk002_FGF2 Category: Tags: , , ,

Description

Fibroblast growth factor 2 (FGF2) or basic FGF  is used to support the maintenance of human embryonic stem cells and proliferation and differentiation of induced pluripotent and mesenchymal stem cells. FGF2 from zebrafish has been used extensively to support the maintenance of human stem cells (1–3).

Mature domain of zebrafish FGF2 (residues 2-154, Uniprot: B3DGE3) expressed in E.coli and purified to homogeneity as described in Ludwig et al. (2)
Protein is provided in PBS without carrier protein at 2-10mg/ml.

Please visit our FGF2 protein page for full details and batch specific data.

We take the quality of our products very seriously. All our proteins are produced in-house by our scientists and we understand the potential impact on your work if your growth factors and cytokines are not consistent and of the highest quality.  We provide comprehensive quality data for every batch.

References:
1. Ludwig, T. E. et al. Derivation of human embryonic stem cells in defined conditions. Nat. Biotechnol. 24, 185–187 (2006).
2. Ludwig, T. E. et al. Feeder-independent culture of human embryonic stem cells. Nat. Methods 3, 637–646 (2006).
3. Chen, G., Gulbranson, D. R., Yu, P., Hou, Z. & Thomson, J. A. Thermal stability of fibroblast growth factor protein is a determinant factor in regulating self-renewal, differentiation, and reprogramming in human pluripotent stem cells. Stem Cells 30, 623–30 (2012).

Additional information

Unit size

1000 µg, 500 µg, 100 µg, 50 µg

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  1. Stem cell researcher, University of Oxford, UK

    Admin Stem cell researcher, University of Oxford, UK

    We have also used the FGF2 for pancreatic cancer sphere systems and it seems to support the growth of the cells as we would expect. University of Oxford, UK.

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