Building next generation growth factors for organoid-driven precision medicine: a protein engineering project co-funded by Innovate UK

We were delighted to be awarded Innovate UK funding to address issues of quality and availability of growth factors for use in organoid technologies. The Qkine R&D team are applying a combination of protein expression, refolding optimisation and structure-guided protein engineering to improve the biological properties and quality of proteins such as R-spondins, TGFβ1, members of the BMP and FGF family proteins.