We innovate to produce the best growth factors and provide solutions for the regenerative medicine field. With our emphasis on quality and reproducibility we will provide you with the best possible tools for research and development.

Protein production science

Qkine uses proprietary refolding technologies and protein purification techniques developed at the University of Cambridge to produce high quality growth factors and related proteins. Our technologies enable us to solve scientific challenges such as structural heterogeneity, poor stability and solubility and spurious interactions with other biomolecules, and provide more reliable tools for research and manufacturing.

Structure-guided protein engineering

Structural biochemistry expertise and targeted protein engineering are used to find solutions to biological and process scale-up challenges. We are developing a portfolio of variant cytokines and other growth factors with improved biological properties.  One of our scientific interests is the optimisation of growth factors for organoid culture.

Quality

At Qkine, the quality of our proteins is very important to us. Marko’s group have worked for many years with the stem cell community to supply proteins of the highest quality. We believe that extensive quality control testing and ensuring batch to batch consistency is of the utmost importance.  Strict criteria for protein quality control are used both at the point of manufacture and through the lifetime of the preparation.  These proteins can be tricky to work with so we seek to optimise formulation and storage conditions for each of the proteins we produce to ensure maximal bioactivity.

Qkine partnerships – if you have a growth factor or protein purification challenge you would like to tackle together, please get in touch

We are happy to work on:

  • collaborative projects
  • large, long term projects and custom batch manufacture for critical experiments
  • custom QC or collaborative transfer to GMP
  • Innovate UK application partnering